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Clinical Trial Search Results

Displaying 243 Trials
Trial ID D7900C00001
Sponsor ID

A Phase 1, Open-label Study to Evaluate the Safety, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of MEDI2228 in Subjects with Relapsed/Refractory Multiple Myeloma

Principal Investigator
Mitul Gandhi, MD
Trial ID APG1252SU101
Sponsor ID

A Multi-Center, Phase I/II Study of Combination APG-1252 Plus Paclitaxel in Patients With Relapsed/Refractory Small Cell Lung Cancer

Principal Investigator
Alexander I Spira, MD, PhD, FACP
1 Location
Trial ID 1336-0011
Sponsor ID

An open label phase Ib dose finding study of BI 836880 in combination with BI 754091 to characterize safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy in patients with locally advanced or metastatic non-squamous Non-Small Cell Lung Cancer and in other solid tumors

Trial ID U31402-A-U201
Sponsor ID HERTHENA-Lung01

A Phase 2 Randomized Open-Label Study of Patritumab Deruxtecan (U3-1402) in Subjects With Previously Treated Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer

Principal Investigator
Alexander I Spira, MD, PhD, FACP
1 Location
Trial ID DS1062-A-U301
Sponsor ID TROPION-Lung01

Phase 3 Randomized Study of DS-1062A Versus Docetaxel in Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer Without Actionable Genomic Alterations

Principal Investigator
Alexander I Spira, MD, PhD, FACP
1 Location
Trial ID DS1062-A-U202
Sponsor ID TROPION-Lung05

Phase 2, Single-arm, Open-label Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations and Progressed on or After Kinase Inhibitor Therapy and Platinum Based Chemotherapy

Principal Investigator
Alexander I Spira, MD, PhD, FACP
1 Location
Trial ID D967LC00001
Sponsor ID DESTINY-Gastric03

A Phase 1b/2 Multicenter, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of Trastuzumab Deruxtecan (T-DXd) Monotherapy and Combinations in Adult Participants with HER2-Overexpressing Gastric Cancer

Trial ID 20344
Sponsor ID SGNTUC-019

A Phase 2 Basket Study of Tucatinib in Combination with Trastuzumab in Subjects with Previously Treated, Locally-Advanced Unresectable or Metastatic Solid Tumors Driven by HER2 Alterations

Trial ID 20381
Sponsor ID MYLUNG Part 2

Molecularly Informed Lung Cancer Treatment in a Community Cancer Network: A Pragmatic Prospective RWE Study (MYLUNG Consortium: Part 2)

Principal Investigator
Alexander I Spira, MD, PhD, FACP
5 Locations
Trial ID 20331
Sponsor ID VS-6766-202

A Phase 2 Study of VS-6766 (Dual RAF/MEK Inhibitor) as a Single Agent and in Combination with Defactinib (FAK Inhibitor) in Recurrent KRAS-Mutant (KRAS-MT) Non-Small Cell Lung Cancer (NSCLC)

Principal Investigator
Alexander I Spira, MD, PhD, FACP
5 Locations
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