WEATHER ALERT: January 25, 2026 (5:15 PM): We are actively monitoring the weather in our area to ensure patient and staff safety. Our offices will be CLOSED on Monday (January 26) with an ON-TIME OPENING on Tuesday (January 27). Patients in active cancer treatment will continue to be prioritized to ensure continuity of care. If you are undergoing active cancer treatment, a team member will reach out to advise of any changes to your appointment. Please continue to check our website for the latest weather updates. Thank you for your patience and understanding.
A humanized recombinant monoclonal antibody directed against the extracellular dimerization domain of the HER-2 tyrosine kinase receptor. Binding of the antibody to the dimerization domain of the HER-2 tyrosine kinase receptor protein directly inhibits the ability of the HER-2 tyrosine kinase receptor protein (the most common pairing partner) to dimerize with other HER tyrosine kinase receptor proteins; inhibiting receptor protein dimerization prevents the activation of HER signaling pathways, resulting in tumor cell apoptosis. Check for active clinical trials using this agent. (NCI Thesaurus)