Alex Spira, M.D., PhD, F.A.C.P.

VCS Physicians

Alex Spira, M.D., PhD, F.A.C.P. Headshot

Getting a diagnosis of cancer is the most challenging thing any patient and family will have to go through. My job is to provide the most comprehensive options for patients, with state-of-the-art care and compassion.

Primary Location:

Fairfax Office
Position

Medical Oncologist

Board Certification

Medical Oncology and Internal Medicine

Fellowship

Johns Hopkins Hospital, Medical Oncology

Internship

Hospital of the University of Pennsylvania

Residency

Hospital of the University of Pennsylvania

Medical School

New York University School of Medicine

College

Harvard University

Dr. Alex Spira earned his medical degree from the New York University School of Medicine. He then went on to complete his internship and residency at the Hospital of the University of Pennsylvania, and his medical oncology fellowship at Johns Hopkins Hospital. During his training, Dr. Spira was granted many awards and honors, and he completed several specialized fellowship programs. Among these honors were the National Institutes of Health Medical Scientist Training Program Fellowship (1990-1997), Merck Corporation Scholarship (1995-1995), Pediatric AIDS Foundation Fellowship (1993- 1995) and Harvard University Scholarship (1987-1990). Dr. Spira has also received his PhD from the New York School of Arts and Sciences.

As Director of the Virginia Cancer Specialists (VCS) Research Institute and the Phase I Trial Program, Dr. Spira is actively involved in advancing medicine and offering targeted treatment options for patients. Although his research interests are numerous, Dr. Spira particularly enjoys studying immunotherapy, personalized medicine, GI, thoracic and lung cancer and sarcomas. Dr. Spira is also Co-Chair of the USOncology Thoracic Oncology Committee, Chair of the USOncology Research Executive Committee, and member of the USOncology National Policy Board Executive Committee. Dr. Spira is a faculty member at Johns Hopkins School of Medicine, and serves as Assistant Professor of Oncology.

Throughout his career, Dr. Spira has been recognized as a Top Doctor in Northern Virginia Magazine and Washingtonian magazine for multiple years. In 2014, he received the prestigious “Castle Connolly America’s Top Doctor” award. In his spare time, Dr. Spira enjoys spending time with his family, coaching children’s sports, cycling, and cheering on his favorite New York sports teams.

 


 

Practice Blog

October 8, 2018

Advancements in Science and Cancer Care Research Announced at the US Oncology Research 17th Annual Science Forum - Dr. Alex Spira

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September 25, 2018

Co Author Alex Spira, MD - Lung Cancer Study Treatment Option for ALK Positive Lung Cancer Patients

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September 20, 2018

Alex Spira, M.D., PhD, F.A.C.P. receives award for his work in Lung Cancer

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Physician Publications

September 25, 2018

Brigatinib versus Crizotinib in ALK-Positive Non–Small-Cell Lung Cancer

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March 9, 2016

Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial

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September 14, 2015

Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial

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More Publications by Alex Spira, M.D., PhD, F.A.C.P.

June 3, 2013

START: A phase III study of L-BLP25 cancer immunotherapy for unresectable stage III non-small cell lung cancer.

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February 1, 2013

Cabozantinib in Patients With Advanced Prostate Cancer: Results of a Phase II Randomized Discontinuation Trial

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January 2, 2013

Expert Insight: Adjuvant Therapy Fails for High-Risk Soft Tissue Sarcoma

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June 1, 2012

Phase II study of two eribulin regimens in combination with erlotinib in patients (pts) with previously treated advanced non-small cell lung cancer

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April 16, 2012

Randomized Phase II Trial of Erlotinib With and Without Entinostat in Patients With Advanced Non-Small-Cell Lung Cancer Who Progressed on Prior Chemotherapy

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January 1, 2012

Clinical trial design in the age of molecular profiling.

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September 8, 2011

A phase II study of eribulin mesylate (E7389) in patients with advanced, previously treated non-small-cell lung cancer.

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June 1, 2011

Results of a phase II study of single-agent sunitinib in elderly non-small cell lung cancer patients

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June 1, 2011

Clinical outcome of single agent volasertib (BI 6727) as second-line treatment of patients (pts) with advanced or metastatic urothelial cancer (UC).

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June 1, 2011

Cabozantinib (XL184) in metastatic castration-resistant prostate cancer (mCRPC): Results from a phase II randomized discontinuation trial.

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December 4, 2010

Serotonin Dysregulation Correlates with Both Bone and Active Disease In Multiple Myeloma.

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December 1, 2010

Phase I Trial of Oxaliplatin, Infusional 5-Fluorouracil, and Leucovorin (FOLFOX4) With Erlotinib and Bevacizumab in Colorectal Cancer.

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December 3, 2009

Use of an ex vivo multiplexed signal pathway inhibitor treatment to reveal sensitivity of myeloma and nonmyeloma bone marrow cell populations.

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December 1, 2009

Phase II trial of nanoparticle albumin-bound paclitaxel, carboplatin, and bevacizumab in first-line patients with advanced nonsquamous non-small cell lung cancer.

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January 22, 2004

Multidisciplinary Management of Lung Cancer

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January 1, 2002

The use of Chemotherapy in Soft Tissue Sarcomas

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Primary Location

Fairfax Office Office

Fairfax Office

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Other Locations

Awards

October 23, 2018

November 1, 2017
Washingtonian Magazne Top Doctors 2017

Washingtonian Magazne Top Doctors 2017


March 9, 2016
Washingtonian Magazine

Washingtonian Top Doctor 2016


September 1, 2015
Washingtonian Magazine

Washingtonian Top Doctor 2015


February 1, 2015
Northern Virginia Magazine

Top Doctor 2015


January 31, 2014
Northern Virginia Magazine

Top Doctor 2014


December 31, 2013
Washingtonian Magazine

Top Doctor 2014


December 31, 2013
Northern Virginia Magazine

Top Doctor 2014


December 31, 2013
Castle Connolly

America’s Top Doctor 2014


January 31, 2013
Northern Virginia Magazine

Top Doctor 2013