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Alexander I. Spira MD, PhD, FACP, FASCO

Medical Oncologist, Virginia Cancer Specialists Research Institute

Alex Spira Bio Photo 2021

Alexander I. Spira MD, PhD, FACP, FASCO

Board Certifications

Medical Oncology

Special Interests

Thoracic/Lung Cancer, Sarcomas, Clinical Trials

Patient Reviews
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Fellowship

Johns Hopkins Hospital, Medical Oncology

Medical School

New York University School of Medicine

Residency

Hospital of the University of Pennsylvania

College

Harvard University

Virginia Cancer Specialists office exterior at dusk
Address
8613 Route 29
Fairfax, VA 22031
Hours
Monday through Friday
8:30 a.m. to 5:00 p.m
Phone
quote
TESTIMONIAL

Getting a diagnosis of cancer is the most challenging thing any patient and family will have to go through. My job is to provide the most comprehensive options for patients, with state-of-the-art care and compassion.

Awards

Castle Connolly – 3 Years of Excellence – 2026
Castle Connolly #1 Physician Practice – 2025
Castle Connolly #1 Physician Practice – 2024
Virginia Top Doctor – 2025
Virginia Living Magazine Top Doctors – 2018
Northern Virginia Magazine Top Doctor – 2026
Northern Virginia Magazine Top Doctor – 2025
Northern Virginia Magazine Top Doctor – 2024
Northern Virginia Magazine Top Doctor – 2023
Northern Virginia Magazine Top Doctor – 2022
Northern Virginia Magazine Top Doctor – 2021
Northern Virginia Magazine Top Doctor – 2020
Northern Virginia Magazine Top Doctor – 2019
Northern Virginia Magazine Top Doctor – 2018
Arlington Magazine Awards Top Doctor – 2024
Washingtonian Top Doctor – 2025
Washingtonian Top Doctor – 2024
Washingtonian Magazine Top Doctor – 2023
Washingtonian Magazine Top Doctor – 2021
Washingtonian Magazine Top Doctor – 2020
Washingtonian Magazine Top Doctor – 2019
Washingtonian Magazine Top Doctor – 2018

Biography

Alexander I. Spira MD, PhD, FACP, FASCO

Co-Director, Virginia Cancer Specialists Research Institute; Director, Virginia Cancer Specialists Thoracic and Phase I Program; Chief Scientific Officer, NEXT Oncology; Clinical Assistant Professor, Johns Hopkins

Dr. Alexander Spira earned his medical degree from the New York University School of Medicine. He then went on to complete his internship and residency at the Hospital of the University of Pennsylvania, and his medical oncology fellowship at Johns Hopkins Hospital. During his training, Dr. Spira was granted many awards and honors, and he completed several specialized fellowship programs. Among these honors were the National Institutes of Health Medical Scientist Training Program Fellowship (1990-1997), Merck Corporation Scholarship (1995-1995), Pediatric AIDS Foundation Fellowship (1993- 1995) and Harvard University Scholarship (1987-1990). Dr. Spira has also received his PhD from the New York School of Arts and Sciences.

As Director of the Virginia Cancer Specialists Research Institute and the Phase I Trial Program, Dr. Spira is actively involved in advancing medicine and offering targeted treatment options for patients. Although his research interests are numerous, Dr. Spira particularly enjoys studying immunotherapy, personalized medicine, GI, thoracic and lung cancer and sarcomas. Dr. Spira is Chief Scientific Officer of NEXT Oncology, as well as Co-Chair of the US Oncology Thoracic Oncology Committee, Chair of the US Oncology Research Executive Committee, and member of the US Oncology National Policy Board Executive Committee. Dr. Spira is a faculty member at Johns Hopkins School of Medicine and serves as Assistant Professor of Oncology.

Throughout his career, Dr. Spira has been recognized as a Top Doctor in Northern Virginia Magazine and Washingtonian magazine for multiple years. In 2014, he received the prestigious “Castle Connolly America’s Top Doctor” award. In his spare time, Dr. Spira enjoys spending time with his family, coaching children’s sports, cycling, and cheering on his favorite New York sports teams.

Physician Publications

Rinad Bsharat

March 29, 2022

Diagnosed as a Young Adult I had already put down my deposit for law school

New OncoTalks Episode: Advancing Biomarker Testing in NSCLC – Dr. Alexander I. Spira, MD, PhD, FACP, FASCO

February 9, 2026

Virginia Cancer Specialists is pleased to share a new episode of OncoTalks featuring our own

Adagrasib in Non–Small-Cell Lung Cancer Harboring a KRASG12C Mutation

June 3, 2022

Adagrasib Induces Promising Efficacy, Deep Responses in KRAS G12C NSCLC

June 3, 2022

KRAS Inhibitor Shrinks Tumors in Over 40% of NSCLC Patients

June 3, 2022

Dr. Spira on the Potential Role of Adagrasib in NSCLC

June 3, 2022

What Patients Say

Locations

8613 Route 29

Fairfax, VA 22031

703.280.9596

Ready to Make an Appointment?

If you have questions about whether this treatment or service may be right for you, make an appointment with the Virginia Cancer Specialists team.