Virginia Cancer Specialists first patient successfully completes Cycle 1 of Treatment with PCM-075 combination with Low Dose Cytarabine (LDAC) AML Trial

VCS Practice Blog

March 06, 2018
Virginia Cancer Specialists » VCS Practice News » Clinical Trials and Research » VCS Practice News » The Research Institute » Virginia Cancer Specialists first patient successfully completes Cycle 1 of Treatment with PCM-075 combination with Low Dose Cytarabine (LDAC) AML Trial

Clinical Trial – Trovagene Announces First Patient Successfully Completes Cycle 1 of Treatment with PCM-075 in Combination with Low Dose Cytarabine (LDAC) in AML Trial

Trovagene, Inc. (NASDAQ: TROV), a precision medicine biotechnology company, developing targeted cancer therapeutics, today announced that the initial patient successfully completed the first cycle 1 of treatment in its Phase 1b/2 multicenter trial of PCM-075 in combination with low-dose cytarabine (LDAC) in patients with Acute Myeloid Leukemia (AML). The patient tolerated the combination well and correlative analyses of blood samples, taken at specified time points, also indicated activity on leukemic blood cells.

“Our first patient on PCM-075 appears to be tolerating the drug regimen well and the observed decrease of blood leukemic cells during the treatment cycle is encouraging,” said Alex Spira, MD, PhD, FACP, Director of The Virginia Cancer Specialists Research Institute.

Acute Myeloid Leukemia (AML)

More… Read the Complete Press Release Here

 

Array
(
    [0] => Array
        (
            [acf_fc_layout] => physician_information
            [title] => 
            [display_all] => 1
            [stretch_to_fit] => 
            [hide_search] => 1
            [add_url_to_image] => 1
            [manual_sorting] => 
            [physicians] => Array
                (
                    [0] => WP_Post Object
                        (
                            [ID] => 547
                            [post_author] => 2
                            [post_date] => 2017-09-08 15:33:13
                            [post_date_gmt] => 2017-09-08 15:33:13
                            [post_content] => Dr. Alex Spira earned his medical degree from the New York University School of Medicine. He then went on to complete his internship and residency at the Hospital of the University of Pennsylvania, and his medical oncology fellowship at Johns Hopkins Hospital. During his training, Dr. Spira was granted many awards and honors, and he completed several specialized fellowship programs. Among these honors were the National Institutes of Health Medical Scientist Training Program Fellowship (1990-1997), Merck Corporation Scholarship (1995-1995), Pediatric AIDS Foundation Fellowship (1993- 1995) and Harvard University Scholarship (1987-1990). Dr. Spira has also received his PhD from the New York School of Arts and Sciences.

As Director of the Virginia Cancer Specialists (VCS) Research Institute and the Phase I Trial Program, Dr. Spira is actively involved in advancing medicine and offering targeted treatment options for patients. Although his research interests are numerous, Dr. Spira particularly enjoys studying immunotherapy, personalized medicine, GI, thoracic and lung cancer and sarcomas. Dr. Spira is also Co-Chair of the USOncology Thoracic Oncology Committee, Chair of the USOncology Research Executive Committee, and member of the USOncology National Policy Board Executive Committee. Dr. Spira is a faculty member at Johns Hopkins School of Medicine, and serves as Assistant Professor of Oncology.

Throughout his career, Dr. Spira has been recognized as a Top Doctor in Northern Virginia Magazine and Washingtonian magazine for multiple years. In 2014, he received the prestigious “Castle Connolly America’s Top Doctor” award. In his spare time, Dr. Spira enjoys spending time with his family, coaching children’s sports, cycling, and cheering on his favorite New York sports teams.


 


  [post_title] => Alex Spira, M.D., PhD, F.A.C.P. [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => alex-spira-m-d-phd-f-a-c-p [to_ping] => [pinged] => [post_modified] => 2019-03-12 13:02:26 [post_modified_gmt] => 2019-03-12 13:02:26 [post_content_filtered] => [post_parent] => 0 [guid] => http://vacs.wpengine.com/?post_type=physician&p=547 [menu_order] => 0 [post_type] => physician [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [page_builder] => 1 [index] => 0 ) )