Language
Select Language

Radiopharmaceutical Treatment Provides Hope for Prostate Cancer Patients

January 31, 2023

Men discussing prostate cancer awareness

James McKinney has been battling prostate cancer for over eight years. After receiving chemotherapy, radiation therapy, and participating in clinical trials, he felt his options for treatment were becoming limited. But a new targeted radiopharmaceutical therapy has been a game changer.

“I just feel relieved,” said McKinney. “This is probably the best I’ve felt in years.”

Radiopharmaceuticals are drugs that contain a radioactive isotope and are used to treat cancer. Recent research in radiopharmaceuticals has led to significant developments for prostate cancer patients whose cancer has spread and become resistant to other forms of treatment. Virginia Cancer Specialists is proud to offer a leading-edge treatment combining the use of PET scans and a new therapy targeting prostate-specific membrane antigen (PSMA)-positive cancer cells in men with advanced prostate cancer.

“You don’t know what tomorrow’s going to bring, we just want to enjoy our lives. I don’t know how to thank Dr. Sibley and his staff for getting my life back.”—James McKinney

New Treatment Identifies and Targets Treatment-Resistant Cancer Cells

The new therapy, which was approved by the US Food and Drug Administration in March 2022, uses a tracing agent (ligand) that attaches to PSMA, a protein on the surface of most prostate cancer cells. If this tracer binds to the cancer cells, they light up on a PET/CT Scan and patients are then eligible for a drug called Pluvicto™. Pluvicto is injected into the bloodstream to deliver targeted radiation to cancer cells throughout the body that express PSMA. The treatment targets bone, nodal and visceral metastases.

“With this new treatment, we’re seeing significant improvement in progression-free survival,” said Dr. Gregory Sibley, MD, a radiation oncologist at Virginia Cancer Specialists. “Patients are living longer and better, usually with no significant side effects. I’m thrilled that Virginia Cancer Specialists is able to provide this option for patients in our community.”

The treatment is currently approved for advanced-stage prostate cancers that have become resistant to other treatments. Dr. Sibley says there is ongoing research is to look at the effects of introducing this therapy at an earlier point in treatment.

Improving Quality of Life with Cancer

McKinney is one of the first patients in the Northern Virginia area to complete all 6 cycles of the new treatment. Now, he says he and his wife plan to enjoy their retirement by traveling and spending time with their adult children.

“When you’re in treatment every six weeks, you have to be cautious. This has given us an opportunity to not be as worried as we used to be,” said McKinney. “You don’t know what tomorrow’s going to bring, we just want to enjoy our lives. I don’t know how to thank Dr. Sibley and his staff for getting my life back.”

Call Virginia Cancer Specialists for Information on Prostate Cancer Treatment

The prostate cancer specialists at Virginia Cancer Specialists work with you to create the optimal treatment plan for your prostate cancer. For more information on these new advancements in prostate cancer treatment, please contact us.

Men discussing prostate cancer awareness

Recent Posts

About Virginia Cancer Specialists

Virginia Cancer Specialists, the largest private cancer practice in Northern Virginia, was recognized in 2024 and 2025 as the #1 physician practice in Virginia with the most Castle Connolly top doctors in cancer care and across all medical specialties. It features a world-class treatment team fighting cancer and diseases of the blood, offering access to the most current treatment protocols, clinical trials, and comprehensive care. Its fully staffed, comprehensive clinical research program also includes a dedicated research facility for Phase I clinical trials—the Virginia Cancer Specialists Research Institute, the largest of its kind in the Mid-Atlantic region. The practice offers medical oncology, radiation oncology, musculoskeletal tumor surgery, breast surgery, thoracic surgery, genetic counseling, palliative care, oncology nurse navigators, oncology infusion nurses, oncology pharmacists, social workers, dietitians, and laboratory technicians. Virginia Cancer Specialists is part of The US Oncology Network. This collaboration unites the practice with more than 1,400 independent physicians and research and data from thousands of cancer patients in clinical trials across the country. Virginia Cancer Specialists also participates in clinical trials through US Oncology Research, which has played a role in more than 100 FDA-approved cancer therapies. For more information, visit USOncology.com. For more information about Virginia Cancer Specialists, visit: VirginiaCancerSpecialists.com

The Network is supported by McKesson Corporation, a global leader in healthcare solutions.

SOURCE Virginia Cancer Specialist

Ready to Make an Appointment?

If you have questions about whether this treatment or service may be right for you, make an appointment with the Virginia Cancer Specialists team.